Promethazine dm

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Promethazine is a first-generation antihistamine, sedative, and antiemetic used to treat allergies, sleeplessness, and nausea. It is marketed under several trade names, including Phenergan. It can also be used to sedate patients who are nervous or worried, which has led to some recreational use (particularly with codeine). It may also help with some common cold symptoms. Promethazine can be administered intramuscularly (IM), orally (oral), or as a rectal suppository.

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Promethazine frequently causes sleepiness and confusion as adverse effects, which can be exacerbated by alcohol or other sedatives. The safety of promethazine use for the fetus during pregnancy or lactation is unknown. Because promethazine may have adverse effects on breathing, it is not advised for use in children younger than two. Because of the possibility of skin injury, promethazine injections into veins are not advised. Promethazine belongs to the class of drugs known as phenothiazine. Its sedative effects are also caused by its potent anticholinergic properties. This implies that hazardous or excessive dosages may likewise have deliriant effects.

In the 1940s, a group of scientists from Rhône-Poulenc laboratories created promethazine. In 1951, the United States authorized its usage for medical purposes. It is a generic drug that is sold under numerous brand names all over the world. With more over 2 million prescriptions, it ranked as the 198th most prescribed drug in the US in 2022. With more than 1 million prescriptions, the combination with dextromethorphan was the 260th most prescribed drug in the US in 2022.

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Promethazine 25mg  is used to prevent and treat nausea and vomiting related to certain conditions (such as before/after surgery, motion sickness). It is also used to treat allergy symptoms such as rash, itching, and runny nose. It may be used to help you feel sleepy/relaxed before and after surgery or to help certain opioid pain relievers (such as meperidine) work better. It may also be used for a short time to treat a runny nose due to the common cold. Promethazine is an antihistamine and works by blocking a certain natural substance (histamine) that your body makes during an allergic reaction.

Its other effects (such as anti-nausea, calming, pain relief) may work by affecting other natural substances (such as acetylcholine) and by acting directly on certain parts of the brain. Cough-and-cold products have not been shown to be safe or effective in children younger than 6 years. Therefore, do not use this product to treat cold symptoms in children younger than 6 years unless specifically directed by the doctor. Some products (such as long-acting tablets/capsules) are not recommended for use in children younger than 12 years.

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Ask your doctor or pharmacist for more details about using your product safely. Promethazine 25mg is not cure or shorten the length of the common cold and may cause serious side effects. To decrease the risk for serious side effects, carefully follow all dosage directions. Do not give other cough-and-cold medication that might contain the same or similar ingredients (see also Drug Interactions section). Ask the doctor or pharmacist about other ways to relieve cough and cold symptoms (such as drinking enough fluids, using a humidifier or saline nose drops/spray).

Read the Patient Information Leaflet if available from your pharmacist before you start taking Promethazine 25mg and each time you get a refill. If you have any questions, ask your doctor or pharmacist.

Take this medication by mouth with or without food as directed by your doctor, usually 2 to 4 times daily. For motion sickness, the first dose of Promethazine 25mg should be taken 30 to 60 minutes before beginning travel. For allergies, this medication may be taken once daily at bedtime to avoid being drowsy during the day. When used before surgery, promethazine may be taken the night before or just before the procedure and may be continued afterwards as directed.

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If you are using the liquid form of this medication, carefully measure the dose using a special measuring device/spoon. Do not use a household spoon because you may not get the correct dose. The dosage is based on your age, medical condition, and response to treatment. In children, the dosage may also be based on weight. Do not increase your dose or take this medication more often than directed.